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Plant Extracts: Ushering In A New Era Of Natural Molecules In The Pharmaceutical Industry
2025-04-24
The dual assistance of national policies and market demand. There is a clear plan to establish a high-quality and efficient traditional Chinese medicine service system by 2025, promoting the improvement of traditional Chinese medicine quality and industrial promotion projects. In the international market, China's exports of plant extracts continue to lead, and it is worth noting that the concept of sustainable development is reshaping the industry chain. Shaanxi, Yunnan and other production areas rely on traditional Chinese medicine resources to form a full industry chain cluster from planting to extraction; The Yangtze River Delta region focuses on high value-added products and builds a technology intensive industrial belt.
I.Pharmaceutical Applications: A Leap from Traditional to Modern
The value of plant extracts in the pharmaceutical industry goes far beyond the classic narratives of artemisinin anti malaria and paclitaxel anti-cancer. Yatai Pharmaceutical has overcome the industrial production difficulties of ginsenoside Rg3 through 10 years of research and development. Its Shenyi capsule (oral targeted anti-tumor drug) won the second prize of National Technical Invention Award in 2013.
Supercritical technology has expanded its application boundaries: flavonoids and lactones extracted from Ginkgo biloba leaves, and capsaicin purified from chili powder, these high value-added products are becoming important Raw Materials for new drug development.
II.Medical breakthrough from 'single target' to 'systematic intervention'
Plant extracts, with their synergistic effect of multiple components, break through the limitations of traditional single target drug therapy and provide systematic solutions for complex diseases, sparking a wave of change in multiple medical fields.
1. Metabolic diseases: targeting the systemic metabolic network
In the field of diabetes treatment, traditional drugs focus on a single target of insulin secretion or glucose regulation, while plant extracts show unique multi-dimensional regulation ability.
For non-alcoholic fatty liver disease, silymarin phospholipid complex can not only activate the PPAR α/γ pathway, promote fat metabolism, but also protect liver cells by regulating oxidative stress and inflammatory response.
2. Tumor treatment: building a multidimensional anti-cancer defense line
In tumor treatment, plant extracts can directly inhibit tumor cell proliferation, regulate the body's Immune System, and overcome drug resistance through multi-target synergy.
3. Neurodegenerative diseases: repairing the neuroecosystem
The pathogenesis of neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease is complex, and single target drugs are difficult to achieve ideal therapeutic effects. After treatment with nanocrystal technology, huperzine A not only efficiently inhibits acetylcholinesterase and increases neurotransmitter concentration, but also intervenes in disease progression from multiple levels by regulating Tau Protein Phosphorylation and inhibiting β - amyloid protein aggregation.
As classic cases such as paclitaxel and artemisinin become a footnote in history, plant extracts are reshaping the modern pharmaceutical landscape through technologies such as synthetic biology and AI screening. From traditional herbs in Himalayan rock fissures to molecular regulation in laboratories, this policy driven industrial transformation is evolving into a new paradigm of "precision medicine+green manufacturing" empowered by technology.
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