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Natural Power Upgrades Again: Ligustri lucidi fructus Extract Leads New Trends in the Health Industry
2025-04-14
Nowadays, with the development of modern separation technology, the active ingredients extracted from Ligustrum lucidum fruit by scientists are becoming a new focus in the field of health. Research has shown that the compounds rich in it, such as oleanolic acid and Ligustrum lucidum glycosides, have unique biological activities, especially showing significant potential in antioxidant, immune regulation, and neuroprotection. This millennium long medicinal heritage is being revitalized through clinical trials and basic research.
I.Mechanism Decoding: Multi Dimensional Guardians at the Cellular Level
The latest research reveals that the mechanism of action of Ligustri lucidi fructus Extract far exceeds expectations. Its antioxidant capacity can eliminate 20 times more free radicals than vitamin C, acting like a "cell cleaner" to delay aging in the body; In terms of immune regulation, it can activate macrophage activity, enhance NK cell toxicity, and provide new ideas for cancer adjuvant therapy. What is even more remarkable is its intervention effect on neurodegenerative diseases. These multi-target mechanisms of action make them versatile players in the era of systems biology.
II.Pharmacological Effects and Clinical Value
Ligustri lucidi fructus Extract exerts diverse pharmacological effects through multi-target mechanisms:
Liver protection: Oleanolic acid can inhibit carbon tetrachloride induced liver fibrosis, reduce serum alanine aminotransferase (SGPT) levels, and repair liver cell damage.
Immune regulation: Polysaccharides significantly enhance T lymphocyte activity and macrophage phagocytic ability, reversing immune suppression caused by chemotherapy.
Anti inflammatory and anti allergic: Inhibits histamine release and prostaglandin synthesis, and has inhibitory effects on type I-IV allergic reactions.
Reducing blood sugar and regulating lipid: oleanolic acid can reduce blood sugar by inhibiting gluconeogenesis, and reduce serum cholesterol to prevent atherosclerosis.
Anti cancer and anti mutation: Inhibits the growth of cervical cancer U14 strain and reduces cyclophosphamide induced chromosomal damage
III. Expanding Application Areas in Depth
In the field of medicine:
Liver disease treatment: Flavonoids from Ligustrum lucidum significantly alleviate liver fibrosis by inhibiting the TGF - β/Smad pathway.
Bone health: Rhodiola rosea glycoside activates the Wnt/β - catenin pathway, promotes osteoblast differentiation, and prevents osteoporosis.
Cosmetics: Its antioxidant and anti-inflammatory properties make it a core ingredient in anti-aging skincare products.
Functional food: The immune regulatory function of Ligustrum lucidum polysaccharides is used to enhance immunity in beverages and dietary supplements.
IV.Future Trends
Green and intelligent: Promote low-carbon extraction technology and establish a full industry chain traceability system.
Cross border integration: combining gene editing technology to optimize planting varieties and develop targeted delivery formulations.
The scientific value and application potential of Ligustri lucidi fructus Extract reflect the concept of traditional Chinese medicine that "inherits without sticking to the past, and innovates without leaving the roots". With the integration of precision medicine and green production technology, it may become one of the core raw materials for the big health industry, promoting the globalization process of natural medicine.
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