Mountain Silver Flower Extract--- Anti-inflammatory and Antioxidant Effects
2026-05-20 11:07:03
The efficacy of the extract is primarily derived from the following classes of active substances:
Organic Acids: Primarily chlorogenic acid, one of the most active ingredients in Lonicerae Flos. The 2020 edition of the Chinese Pharmacopoeia stipulates its content shall not be less than 2.0%.
Flavonoids: Such as luteolin, nobiletin, etc., which possess antioxidant effects.
Triterpenoid Saponins: Such as macranthoidin B, etc. These are the primary characteristic components that distinguish Lonicerae Flos from Lonicerae Japonicae Flos (Honeysuckle). The Pharmacopoeia stipulates the total content of these shall not be less than 5.0%.
1. Main Chemical Constituents
The efficacy of the extract is primarily derived from the following classes of active substances:
Organic Acids: Primarily chlorogenic acid, one of the most active ingredients in Lonicerae Flos. The 2020 edition of the Chinese Pharmacopoeia stipulates its content shall not be less than 2.0%.
Flavonoids: Such as luteolin, nobiletin, etc., which possess antioxidant effects.
2. Core Pharmacological Effects
Research has confirmed that Lonicerae Flos extract exhibits significant effects in the following areas:
Anti-inflammatory Effect: This is its core efficacy. It significantly inhibits the release of Nitric Oxide (NO) and various inflammatory factors (e.g., TNF-α, IL-6). Studies have found that the water-saturated n-butanol fraction of the extract shows the strongest anti-inflammatory activity.
Antioxidant Effect: It effectively scavenges free radicals and protects cells from oxidative damage. Research indicates that the ethyl acetate fraction possesses the strongest antioxidant capacity.
Anti-atherosclerosis: Studies suggest that its flavonoid components can effectively reduce intracellular cholesterol content
Heat-clearing and Detoxifying: Traditional medicine considers it cold in nature and sweet in taste. It is used to treat boils, sores, abscesses, and wind-heat colds.
3. Extraction Process and Quality Control
Common Process: A frequently used technique in laboratories and industry for efficient extraction is the Ultrasound-Assisted Solvent Extraction method.
Reference Parameters: One optimized study showed that using 57% ethanol, with a solid-liquid ratio of 1:10, and ultrasonic extraction at 60°C for 11 minutes, the total phenolic extraction yield can reach approximately 71.08 mg/g.
Identification for Differentiation: Compared to Lonicerae Japonicae Flos (Honeysuckle), besides the different standard for chlorogenic acid content, the total amount of Macranthoidin B and Dipsacoside B must be tested. This is the key distinguishing factor between the two.
Cold Nature: Due to its cold medicinal property, individuals with spleen-stomach deficiency cold (prone to symptoms like diarrhea and stomach pain) should use it with caution.
Lonicera Confusa Extract: Chlorogenic acid 6%~12%, high saponin content; stronger antibacterial and liver-protective effects, mainly produced in southern China.
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