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Chuanxiong rhizoma Extract - Ancient Wisdom of the “Wizard of Blood”
2025-06-17
I: Plant Traceability
Chuanxiong rhizoma Extract is an active ingredient extracted from the dried rhizomes of Ligusticum Chuanxiong, a plant of the Umbelliferae family. Chuanxiong is mainly found in Sichuan, Yunnan, Guizhou, Guangxi, Hubei and other places in China, with Sichuan being the best. Chuanxiong rhizoma Extract are usually prepared by aqueous or alcoholic extraction. Chuanxiong rhizoma Extract is a perennial herb, 40-70 centimeters tall, with well-developed rhizomes that form irregular nodular fist-shaped masses with a strong aroma. It is harvested in summer when the nodal discs on the stems are prominently protruding and slightly purple in color, the sediment is removed, dried in the sun, and then the fibrous roots are removed.
II: The main components of Chuanxiong rhizoma Extract include:
1: Alkaloids: e.g. Chuanxiong Ligusticum Zingibericum, Hesperidin.
2: Organic acids: such as ferulic acid, chlorogenic acid.
3: Phthalides: e.g. ligustilide, psoralenolide, etc.
4: Polysaccharides: composed of glucose, galactose, arabinose, etc..
III: Pharmacological effects
1: Effects on cardiovascular and cerebrovascular system
Vasodilatation: Chuanxiongxizine can relax vascular smooth muscle, dilate coronary arteries, cerebral blood vessels, increase blood flow, and improve myocardial and cerebral ischemia and hypoxia (such as coronary heart disease, cerebral arteriosclerosis, etc.).
Antiplatelet aggregation: ferulic acid can inhibit platelet-activating factor (PAF), reduce blood viscosity, and prevent thrombosis (commonly used in cerebral thrombosis, angina pectoris and other auxiliary treatment).
Protection of vascular endothelium: through antioxidant effect, reduce vascular endothelial damage, slow down the process of atherosclerosis.
2: Anti-inflammatory and analgesic
Ferulic acid and other components can inhibit the release of inflammatory factors (e.g., TNF-alpha, IL-6), reduce inflammatory response, and have a soothing effect on rheumatoid arthritis and headache (e.g., migraine).
3: Regulation of the immune system
Chuanxiong polysaccharide can enhance the activity of immune cells (e.g. macrophages, T-cells) and improve the immunity of the body.
IV: Cross-border applications:
Used in the treatment of coronary heart disease, angina pectoris, cerebral blood supply insufficiency, Chuanxiongxizine injection is used to improve microcirculation to assist in the treatment of ischemic stroke
Health care products: Capsules and tablets based on Chuanxiong rhizoma Extract, claiming to have the efficacy of activating the blood circulation and removing blood stasis, and anti-fatigue, etc.;
Cosmetic products: Added to skincare products, the main focus of the antioxidant, improve the microcirculation of the skin (eg, to lighten the dark circles under the eyes).
With its blood-activating, antioxidant and anti-inflammatory properties, Chuanxiong rhizoma Extract spans a wide range of industries, including medical, health and beauty, and has great potential, especially in the modernization of traditional Chinese medicine and the development of functional products. With the advancement of precise extraction technology and clinical validation, its application scenarios will be further expanded in the future.
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