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Atractylodis Macrocephalae Extract: Chlorogenic Acid Is Valued
2024-11-21
Atractylodes is a flowering plant in the Asteraceae family, native to China, known in Chinese medicine as "Bai Zhu", and grown in lush, typhoidal areas such as Zhejiang and Anhui. The plant is known for its thick, knobby roots, which are harvested and processed to make the medicinal extracts we value today. The dried root is commonly used to create extracts, tinctures, powders and granules to encapsulate its therapeutic benefits. Atractylodes are well documented in classical medical texts. The first mention of Atractylodes was made as early as the Han Dynasty in the classical text, Shennong Ben Cao Jing (Classic of the Materia Medica of the Divine Husbandman).
Atractylodes macrocephala Extracts are rich in bioactive compounds such as polysaccharides, sesquiterpenes and volatile oils, which together give Atractylodes macrocephala its health-promoting properties. The polysaccharides are known for their immunomodulatory properties, while the sesquiterpenoids and essential oil components have anti-inflammatory and antioxidant properties. These bioactive components form the core of the extract's therapeutic potential.
In recent years, research on the composition of Atractylodes macrocephala has focussed on the volatile oils, polysaccharides and internal lipids. Modern studies have found that Atractylodes macrocephala contains a variety of organic acids at the same time, and the phenolic acid components of the plant have been increasingly reported to be antibacterial, anti-infective, etc., and can co-exert pharmacological activities in drugs.
Some scholars used UPLC method to determine the content of neochlorogenic acid, chlorogenic acid and cryptochlorogenic acid in Atractylodes macrocephala of different origins, which provides scientific reference for the establishment of scientific, reasonable and controllable quality control standards for the active ingredients of Atractylodes macrocephala.
The UPLC method was used to test 15 batches of Atractylodes macrocephala samples of different origins:
The UPLC method was used to test 15 batches of Atractylodes macrocephala samples of different origins, each weighing about 1 g of Atractylodes macrocephala powder, placed in a flask, precision adding 30% ethanol 20 ml, weighing the mass, refluxed in a water bath for 40 min, cooled, then weighing the mass, and then replenish the loss of mass with 30% ethanol, mixing, filtration, and take the filtrate, as a solution for the test article. The total mass fractions of neochlorogenic acid, chlorogenic acid and cryptochlorogenic acid of 15 batches of herbs were measured in the range of 0.19-2.14 mg/g.
