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Niacinamide, the controversial whitening masterpiece

2025-01-16

As the saying goes, “there's a lot of right and wrong in the world of whitening,” and as a big name in the whitening industry, the controversy over niacinamide can be said to be very numerous. Niacinamide is a water-soluble vitamin, one of the important members of the vitamin B family, which can be transformed from niacin (vitamin B3+) in the body, both have a vitamin effect. 

Niacinamide can be taken as a medication due to its pharmacologic effects (clinically used to combat roughness and problems such as stomatitis and lingual inflammation, sick sinus node syndrome, and atrioventricular conduction block). Due to its antioxidant properties it can slow down or block the formation of melanin, or act on melanin-producing cells, and can be used as an additive in whitening cosmetics. The general allowable level of niacinamide added to cosmetics is 0.5-2.0%. Excessive amounts of niacinamide may have negative effects on the human liver.

Niacinamide分子式
Niacinamide Whitening Research
The whitening mechanism of niacinamide is obviously different from that of traditional whitening ingredients that achieve skin whitening simply by inhibiting the activity of complexinase+ and reducing the production of skin melanin, or blemish-removing ingredients that achieve whitening through the reduction of pigmentation and the amount of skin melanin deposition. He inhibits the formation of melanin particles by inhibiting the formation of melanin particles, and its upward movement to the epidermal cells to the stratum corneum, affecting the color of the skin or the formation of pigmentation of this stage before playing a great role in effectively inhibiting the transmission of melanin to the stratum corneum cells, when some of the melanin inevitably reaches the surface of the skin, niacinamide can accelerate the rate of renewal of the skin cells by accelerating the skin cells and thus promote the shedding of the melanin-containing cells.

At present, the application of niacinamide is becoming more and more widespread, especially as one of the raw materials for whitening skin care cosmetics, favored by the domestic and foreign daily chemical industry, but the toxicity and side effects of niacinamide have also been questioned.

Whitening
Question 1: Niacinamide is irritating to use and easily allergic?
Niacinamide, like any vitamin or drug, has two sides, too much is not enough. Excessive use or niacinamide impurity (impurities) can cause skin irritation. In other words, the purity of the raw material and the concentration of niacinamide used will affect its action. The preparation process of high purity niacinamide also determines the price and effectiveness of the formulated product. This is one of the main reasons why the price of niacinamide products on the market varies so much. In addition, niacinamide has an exfoliating effect similar to that of fruit acids, and although its chemical exfoliation effect is weaker than that of fruit acids, it still has a certain degree of irritation to the skin, so many people feel redness, tingling, allergies and other mild sensitivities after use.
Question 2: Will I grow hair after using niacinamide?
At present, there is no data showing that the human body accelerates the growth of surface hair after using niacinamide. Although there is often feedback from women that their facial hair production is accelerated after using niacinamide cosmetics, we have no way of confirming this, nor do we have any relevant research data to support this. Therefore, the response of human hair to niacinamide cannot be determined.

Question 3: Can I not use Niacinamide during the day?
Niacinamide can be used during the day. Niacinamide is different from light-sensitive whitening ingredients such as VC, which cannot be protected from light. However, any cosmetic product should always be stored in a cool place away from direct sunlight.
Question 4: Can niacinamide really whiten my skin?
Studies have shown that niacinamide can inhibit the transfer of melanin to the epidermis and accelerate the speed of cell renewal so that melanin can be reduced to achieve a certain whitening effect. And according to many clinical human studies, after using a certain concentration of niacinamide cosmetics for a certain period of time, it can be visually or instrumentally detected changes in the color of the epidermis.

Niacinamide