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Diosmin

Brief introduction

First isolated in the 1920s, Diosmin belongs to a class of polyphenolic compounds known as flavonoids, which are renowned for their antioxidant activity. It is predominantly found in the peels of citrus fruits such as oranges and lemons. Diosmin is a phlebotropic drug, which means that it specifically targets the veins and helps improve their tone and elasticity. This unique property makes Diosmin an invaluable component in treatments aimed at alleviating venous diseases and other circulatory system disorders. Diosmin is a naturally occurring flavonoid that is a derivative of another flavonoid, diosmetin. The substance is most abundantly extracted from citrus fruits, though it can also be synthesized in laboratory settings.

    Product Details

    Diosmin is a naturally occurring flavonoid that is primarily sourced from citrus fruits and has gained considerable attention for its potent health benefits. This powerful compound is known for its remarkable vascular-protective and anti-inflammatory properties, making it a widely used ingredient in dietary supplements and pharmaceuticals. Diosmin, often paired with a closely related compound called hesperidin, is utilized to enhance vascular health, particularly in the treatment of chronic venous insufficiency (CVI), hemorrhoids, and varicose veins.Diosmin works by prolonging the effects of norepinephrine on the vein wall, which leads to increased venous tone and reduces the capacity of blood vessels to pool blood. Additionally, Diosmin mitigates inflammation by inhibiting the synthesis and release of inflammatory mediators such as prostaglandins and thromboxane. Its antioxidant properties help scavenge free radicals, thereby protecting cells from oxidative stress.
    Diosmin is primarily employed in the treatment of chronic venous diseases. It is efficacious in reducing symptoms such as leg swelling, pain, and cramps often associated with CVI. Additionally, it is used in the management of hemorrhoidal disease, where it helps reduce the size of hemorrhoids and relieves associated pain and bleeding. Diosmin’s vascular strengthening properties also make it a candidate for treating varicose veins, diabetic retinopathy, and lymphedema.
    Functions: vascular protection,anti-inflammatory and antioxidant,edema management and so on.

    Product specifications

    Product Diosmin
    Specification 95%(HPLC)
    Items Appearance: Greyish-yellow or light yellow hygroscopic Powder
    Odor & Taste: Characteristic
    Boiling: 926.8℃
    Melting Point: 165-169℃
    Loss on Drying: ≤6.0%
    Total Ash: ≤0.2%
      Particle Size (100% through 80 mesh): Conform
    Contaminants Heavy Metals: Conform
    Package Inner packaging: Two layers of food PE transparent plastic waterproof bag  (Customized packaging on request)
    Outer packaging: 25kg/drum

    Product Advantage

    1.Efficacy: Numerous clinical studies have validated the effectiveness of Diosmin in managing venous insufficiencies. Patients report significant improvements in symptoms like leg heaviness, swelling, and pain, substantiating its utility as a first-line treatment for chronic venous disorders.
    2.Safety: Diosmin has an excellent safety profile, with minimal side effects reported. Most adverse reactions are mild and transient, such as gastrointestinal disturbances or headaches, making it suitable for long-term use.
    3.Versatility: Due to its broad spectrum of benefits, Diosmin is versatile in its application, addressing multiple conditions related to poor vascular health. Its anti-inflammatory and antioxidant properties further expand its therapeutic potential.

    Flow Chart of Extract

    Dehydrated Pyridine and Iodine →Dissolution →Synthetic Cream →Filter, Water →Synthesize Crude Products →Dissolution →Filter →Filter Liquor →Crystals →Diosmin Wet Products →Drying →Outer Pack.

    Product Storage

    Store in a well-closed container Away from moisture, light, oxygen.

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